||On July 1, the Trustees of Indiana University establish IU East as one of seven regional campuses. With funds raised by area citizens, the trustees purchase 225 acres of land in Richmond, Indiana.
||633 students enroll for the fall semester.
||Whitewater Hall, the first campus building, officially opens to students. This same year, the university receives accreditation from the North Central Accreditation Association of Schools and Colleges.
||Alexander Schilt is named the first chancellor of IU East.
||Glenn Goerke is named IU East's second chancellor.
||Charlie Nelms is named third chancellor of IU East.
||The IU East Alumni Association is chartered with Greg E. Chamness serving as its founding president.
||Student enrollment increases to nearly 2,200, a more than 50 percent increase over 1985 enrollment.
||Brice E. Hayes Hall is dedicated.
||IU East opens the Connersville Center, an off-campus instructional site, and 400 students enroll.
||David Fulton becomes IU East's fourth chancellor.
||Middlefork Hall is dedicated, and the Indiana General Assembly gives preliminary approval to a fourth campus building to focus on student activities.
||The Henry County Danielson Center, IU East's second off-campus instruction site, opens. This same year, Springwood Hall is dedicated as the fourth building on the Richmond campus.
||IU East celebrates 30 years as an IU campus.
||The Tuition Reciprocity Agreement begins in the fall, allowing Ohio students in Butler, Darke, Mercer, Preble, Shelby and Van Wert counties to attend IU East at in-state tuition rates.
||The Campaign for Community concludes with $2.5 million raised. The campaign funds the establishment of the Center for Entrepreneurship and construction of the Art Gallery and Meijer Artway.
||The Art Gallery opens in Whitewater Hall. More than 2,000 people visit the gallery during the first six months.
- The Master of Science in Education established with its first cohort class.
- Nasser H. Paydar is appointed Interim Chancellor.
- The Quigg Family Foundation Nursing Laboratory and the Reid Hospital & Health Care Services Simulation Lab are dedicated.
- IU East launches intercollegiate athletics in women's volleyball, men's basketball, and men's golf and joins the National Association of Intercollegiate Athletics (NAIA).
- IU East officially becomes the Red Wolves, changing its mascot from the Pioneers.
- Indiana University and Ivy Tech Community College announce a new partnership between IU East and Ivy Tech Community College Richmond to enhance learning opportunities for residents of east central Indiana and west central Ohio.
- As part of its new mission as east central Indiana's leader in baccalaureate education, IU East no longer admits students into associate degree programs.
- The Master of Social Work is approved and becomes IU East's second graduate program.
- Three new sports begin intercollegiate competition: men's cross-country, women's cross-country, and women's golf.
- January - Chancellor Nasser Paydar becomes one of the first university chancellors or presidents on Twitter to help increase the communication level of the campus and to make his leadership style transparent.
- March – IU East establishes the Bachelor of Science in Informatics degree program to provide students the necessary skills for professions centered in information technology. The program enrolled students beginning fall 2009.
- January - Indiana University East is no longer the smallest Indiana University regional campus in terms of credit hours.
- March - IU East receives approval from the Indiana Commission for Higher Education to offer its first graduate degree program at its Ivy Tech Community College site in Lawrenceburg. The Master of Science in Education degree program was available to students in summer 2010.
- March - IU East offers its first graduate degree program at Ivy Tech Community College in Lawrenceburg. The Master of Science in Education provides teaches with local access to an established master’s degree.
- Fall - IU East is continues to experience record-breaking enrollment growth. Student enrollment (3,365) increased by 15.1 percent. The most credit hours (33,411.5) in IU East’s history were taught, an increase of 15.5 percent over fall 2009.
- November - IU East, Vincennes University Jasper, and the Indiana University School of Continuing Studies announce a new partnership between the institutions that provides greater educational opportunities to residents of southern Indiana. Chancellor Paydar and Vincennes University Jasper Assistant Vice President and Dean Alan D. Johnson signed a memorandum of understanding for IU East to provided online degree completion programs to students at the Vincennes University Jasper Campus.
- May - Indiana University East celebrates its 40th anniversary with alumni, the community and campus. IU East launches its commemorative website featuring an event listing, the history of the campus, photo galleries and the opportunity for alumni and friends to share their experiences and memories of IU East.
- May - IU East completed its transition to a full-fledged baccalaureate and master’s degree institution when the final three associate degrees were conferred during the 40th Commencement Ceremony. IU East awarded approximately 2,560 associate degrees since July 1, 1971.
- June – IU East and Reid Hospital & Health Care Services, in collaboration with the Indiana University School of Medicine, created educational opportunities for medical students in Richmond, while providing a connection to the community that could result in more practicing physicians in the east central Indiana area. Students pursuing a medical degree from the IU School of Medicine can now complete their third and fourth-year required clinical clerkships in Richmond.